"Donald Trump is contesting the result," the actor joked during one of his speeches. "He's claiming that a lot of dead people voted, which is a very rude thing to say about the HFPA."
During his first speech, Sacha referred to co-star Maria Bakalova as a "sensation."
The proud Confessions of a Shopaholic star planted one on the actor just before he started his speech.
"Thank you to the all-white Hollywood Foreign Press," Sacha quipped, referring to the controversy over the Golden Globes' voting body. Click here to see how an HFPA member addressed the situation during the telecast.
Isla clearly could not hide her admiration throughout Sacha's award-winning night.
"I've got to say, this movie couldn't have been possible without my co-star, a fresh new talent who came from nowhere and turned out to be a comedy genius," Sacha joked. "I'm talking, of course, about Rudy Giuliani."